3-Iodobenzylguanidine

A guanidine analog with specific affinity for tissues of the sympathetic nervous system and related tumors. The radiolabeled forms are used as antineoplastic agents and radioactive imaging agents. (Merck Index, 12th ed) MIBG serves as a neuron-blocking agent which has a strong affinity for, and retention in, the adrenal medulla and also inhibits ADP-ribosyltransferase.

Also Known As:

Iobenguane; MIBG; 3-Iodobenzylguanidine, 123I Labeled; 3-Iodobenzylguanidine, 125I Labeled; Iobenguane (131I); m-Iodobenzylguanidine; meta-Iodobenzylguanidine; 123I Labeled 3-Iodobenzylguanidine; 125I Labeled 3-Iodobenzylguanidine; 3 Iodobenzylguanidine; 3 Iodobenzylguanidine, 123I Labeled; 3 Iodobenzylguanidine, 125I Labeled; m Iodobenzylguanidine; meta Iodobenzylguanidine; (3-Iodo-(131I)benzyl)guanidine

Pharmalogical Action Categories:

Antineoplastic Agents
Enzyme Inhibitors
Radiopharmaceuticals

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Iodobenzenes
        3-Iodobenzylguanidine: 2197
  - Halogenated Hydrocarbons: 42
    - Iodinated Hydrocarbons
      - Iodobenzenes
        3-Iodobenzylguanidine: 2197
- Amidines: 14
  - Guanidines: 29
    - 3-Iodobenzylguanidine: 2197

A C de Groot Selected Research

A C de Groot Research Topics

Disease

Drug/Important Bio-Agent (IBA)